Police are appealing for information following a collision in Kings Park yesterday that left a man with life-threatening injuries.

Investigators have been told a pedestrian was struck by a car on Kings Road about 6.30pm on Wednesday. A 26-year-old Deer Park man was taken to hospital with life-threatening injuries.

The driver of the car, a 30-year-old Hillside woman, stopped at the scene and assisted police with their inquiries.

Police are yet to establish the exact circumstances surrounding the incident.

Anyone with information, who witnessed the incident or has dash cam footage is being asked to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au