Homicide Squad detectives have charged a 26-year-old Sunshine West man following the death of a man in Braybrook on Saturday night.

Police allege brothers Paul and Sean Duncanson were struck by a car and assaulted on Castley Crescent about 9.30pm.

Paul, 40, was taken to hospital where he later died.

His older brother Sean, 44, was also taken to hospital where he remains in a serious condition.

The 26-year-old Sunshine West man has been charged with the murder of Paul Duncanson and with intentionally causing serious injury to Sean Duncanson.

He was remanded in custody and will appear at the Melbourne Magistrates’ Court on Wednesday.